18 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Sarcoidosis Non-caseating ... Constitutional: Fever ... polyarthritis • Pulmonary ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... Pulmonary and ... #Diagnosis #Management ... #Signs #Symptoms
Sarcoidosis
Stage 1 - Bilateral LAD without involvement of lung parenchyma
Stage 2 - Bilateral LAD with involvement
Sarcoidosis Stage ... gland sweling, fever ... #Diagnosis #Stages ... #Staging #Signs ... #Symptoms #Summary
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... if neutropenic fever ... #management #treatment ... #hematology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
and Management ... caucasian • Symptoms ... Unilateral • Signs ... indicated if NMOSD or sarcoidosis ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... following: • Fever ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
acute respiratory symptoms ... symptomsRheumatologic ... Increased protein level ... normal glucose level ... #Management #Infections
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
workup or TSH level ... if symptoms of ... Pyridostigmine - New diagnosis ... monitoring (vital signs ... ://twitter.com/PulmCrit