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dermatology differential sle management classification dermatomyositis druginduced erythematosus oncology signs symptoms systemic antimda5 antimda5dm antinxp2 antinxp2dm capitis clinical comparison complications
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... gangrenosum • IBD ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... aphthous ulcers, cutaneous ... such as systemic lupus ... strong sign of cutaneous ... #rheumatology #
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
response -> Subacute cutaneous ... inflammation on skin ... Malar (butterfly) Rash ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... signs #symptoms #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Rare (SSA+ for cutaneous ... Prognosis: Usually mild ... comparison #table #rheumatology ... #diagnosis #management
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
Newborn- A 3-week-old ... Somalia, had similar skin ... ringworm, was diagnosed ... #clinical #photo ... #ringworm #derm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Labs/Diagnosis: ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... Strong sign of cutaneous ... , mucositis • Rash ... #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Most common extra cutaneous ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
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