43 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... /arthritis, Skin ... rash ± odynophagia ... #Disease #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Rash • Human ... infection Malar rash ... • Rheumatic fever ... gangrenosum • IBD ... differential #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... with urticarial rash ... maculopapular skin ... #Adult #onset #Stills
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... maculopapular rash ... #Disease #AOSD
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Purpura Fulminans Skin ... Exam 60 year old ... splenectomy 1d chills ... BIDMC Infectious Diseases ... #photo
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... criteria: - Fever ... weeks - Typical skin ... rash: maculopapular ... #Criteria #Diagnosis
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... Legg-Calve-Perthes disease ... • Bursitis • IBD ... - HIV - Lyme disease ... /swelling - Fever
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... infection • Still's ... Scleroderma Thickened skin ... conditions #joint #pain ... #differential #diagnosis
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... Rapid onset of fever ... , chills, hypotension ... chronic liver disease ... legs #clinical #photo
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... sulfa-drug - Skin ... pain - Immunocompromised ... #Diagnosis #