10 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... • Rheumatic fever ... lesions • Discoid lupus ... dermatology #joint #pain ... differential #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Vasculitis (e.g. ... Scleroderma Thickened skin ... conditions #joint #pain ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fever (50%), Depression ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... lesions Abdominal pain ... (20%) Renal disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... 3rd Decade Skin ... : • Joint pain ... , Fever, Serositis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract: abdominal pain ... mucositis - Rash ... gut -> abdominal pain ... , testes -> pain ... , and SLE) • Urinalysis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... tract: Abdominal pain ... , mucositis • Rash ... involvement, abdominal pain
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... malaise) - Muscle pain ... Inflammation and pain ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... Red Flags: • Fever ... lesions • Severe pain ... (lupus, RA, Sjogren's ... cryoglobulins • Skin
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... is the main clinical ... Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
substantial muscle pain ... Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Muscle pain ... , joint pain and