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rheumatology dermatology differential management signs symptoms classification erythema joint physicalexam sle systemic activation algorithm antimda5 antimda5dm arteritis autoimmune causes conditions
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Rash • Human ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... weight loss, and fever ... 3rd Decade Skin ... Clinical Features ... Arthritis: • Joint pain
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: Fever ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... lesions Abdominal pain
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus, ... : • Fevers •
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Inflammation and pain ... Leukocytoclastic vasculitis ... - Lupus - Leukemia
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... burning sensation or pain ... • Goodpasture syndrome ... #dermatology #rash
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... syndromes Clinical ... is the main clinical ... Petechial or purpuric rash ... #Diagnosis #Management
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Red Flags: • Fever ... lesions • Severe pain ... (lupus, RA, Sjogren's ... cryoglobulins • Skin
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... , ranging from mild ... disorders (Systemic lupus ... erythematosus, ... Manifestations #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... : • Clinical triad ... Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus (
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