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differential dermatology rheumatology symptoms pathophysiology sle algorithm autoimmune classification clinical common complications dermatomyositis distribution dm erythematosus manifestations moccasin mucocutaneous myopathy
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... skin of inflamed ... type #clinical #photo
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... purpura: strong sign
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... Herald's atch • Tinea ... #Algorithm #causes
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... -> Heliotrope Rash ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... of shoulder and hip ... , mucositis • Rash ... tract, and often causes
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... dorsal aspect of foot-shoe ... with site, (e.g„ tinea ... #dermatology #rash ... #differential #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... ) • Shawl sign ... statins - probably caused
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