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differential pathophysiology dermatology disease management ra arthritis autoimmune dermatomyositis erythematosus giantcell lupus myositis rheumatoid sle syndrome systemic adult antimda5 antimda5dm
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
patients < 50 yrs old ... ; F>M Signs/Symptoms ... skin lesions ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Diagnosis Framework ... : - Ig A (HSP) ... : • Temporal arteritis ... #rheumatology # ... differential #diagnosis
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Disease, Rheumatoid Vasculitis ... Pulmonary Disease and ILD ... #RA #diagnosis ... #rheumatology #signs ... #symptoms
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... #differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... , Vasculitis, Purpura ... (rare), Arthritis ... #symptoms #diagnosis ... #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... can present with rash ... Classic triad of ILD ... myositis, and arthritis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... and Superficial temporal ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... = vasculitis vs ... required due to skip ... them, but urgent rheumatology ... #Signs #Symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... and Superficial temporal ... , mucositis • Rash ... • Progressive symptoms ... #Rheumatology
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... • Polymorphous rash ... : - Coronary Arteritis ... - Generalized Skin ... #Symptoms #Vasculitis
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