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diagnosis rheumatology dermatology sle erythematosus systemic clinical differential signs stages symptoms syphilis vasculitis activation acute adult algorithm allergy antibiotics antinxp2
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Skin Rash on Physical ... Exam 60 year old ... BIDMC Infectious Diseases ... #Fulminans #Skin ... #photo
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Treatment: • ... Mild disease- Hydroxychloroquine ... #rheumatology #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... rash) • Heart, ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... pain (20%) Renal disease
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis) 55 year old male on tuberculosis treatment
Vasculitis) 55 year old ... on tuberculosis treatment ... Vasculitis #clinical #photo ... #dermatology #skin ... #rash #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... mucositis - Rash ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... such as systemic lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... Photosensitive rash ... CNS • Headache, mild ... Seizures • Strokes Skin
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... sudden onset of a rash ... - Rash: multiple ... - Lupus - Leukemia ... Treatment: - Systemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Prognosis: Usually mild ... Manifestations: Malar rash ... Usual therapeutic management ... Evolution: Chronic disease
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