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diagnosis rheumatology dermatology classification comparison differential management systemic vasculitis activation cryoglobulinemia cryoglobulins dress druginduced drugrelated exanthema flexural hematology intertriginous joint
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... 3rd Decade Skin ... rash • Erythematous ... Clinical Features
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... Demyelinating syndromes ... #erythematosus #
DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... : Painful erythematous ... macules with purpuric ... TEN #comparison #table
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [ ... SLE], AOSD) • Infection
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Prognosis: Usually mild ... Erythematosus ( ... #table #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... : • Clinical triad ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus, ... vasculitis, and SLE
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
well-demarcated, erythematous ... known as baboon syndrome ... , blisters, or purpura ... Washington University ID ... #clinical #photo
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