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rheumatology dermatology differential sle systemic classification activation cryoglobulinemia cryoglobulins dermatologic gpa granulomatosis hematology joint macrophage mas oncology pain polyangiitis rashes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... macules • Erythematous ... Differential Diagnosis ... • Goodpasture syndrome ... #dermatology #rash
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... signs #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... : erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus,
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... CNS • Headache, mild ... Seizures • Strokes Skin ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... reticularis & skin ... Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus (
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Treatment: • Mild ... #SLE #Summary #diagnosis ... #rheumatology #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [ ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... : Erythematous nodules ... , mucositis • Rash ... • Cogan syndrome
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Leukocytoclastic vasculitis ... - Lupus - Leukemia ... cutis Diagnosis
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