13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- (Reiter’s syndrome ... - with the skin ... with Systemic Lupus ... Erythematosus ( ... like “butterfly rash
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
• Systemic Lupus ... Erythematosus ... Sicca) Syndrome ... Henoch-Schonlein Purpura ... #Orthopedics #Causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... Demyelinating syndromes
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Joint pain • Swan ... arthropathy • 90% joints ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... • Giant cell arteritis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... : erythematous nodules ... vesicular eruption - Joints ... mucositis - Rash ... erythematosus,
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Skin ulcers ... Cryoglobulins Cause ... (e.g. systemic lupus ... erythematosus (
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
pancreatitis), joints ... (arthritis), central ... nose (epistaxis), skin ... vesicular rash, ... Nephrocalcinosis causes
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... and pain of the joints ... Causes: - Idiopathic ... - Lupus - Leukemia