13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #pain #skin #rashes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... reticularis & skin ... arthralgia, and arthritis ... (e.g. systemic lupus ... erythematosus (
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... Demyelinating syndromes ... lesions Abdominal pain
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- (Reiter’s syndrome ... - with the skin ... with Systemic Lupus ... Erythematosus ( ... like “butterfly rash
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Pain - Differential ... • Systemic Lupus ... Erythematosus ... Sicca) Syndrome ... Henoch-Schonlein Purpura
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Joint pain • Swan ... arthropathy • 90% joints ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Maculopapular rash ... burning sensation or pain ... • Goodpasture syndrome ... • Giant cell arteritis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... vesicular eruption - Joints ... mucositis - Rash ... erythematosus, ... Serologies for Cryoglobulins
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... • Fever is the main ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Inflammation and pain ... of the joints ( ... - Lupus - Leukemia