19 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... , Vasculitis, Purpura ... Demyelinating syndromes ... #erythematosus # ... signs #symptoms
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... Suggestive of: Lupus ... elevated rim (In POC ... migrans: • Target sign ... Suggestive of systemic
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... erythematosus
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
SKIN RASHES ... Skin rashes ... , erythematous, ... signs of illness ... ; #rash; #vesiculobullous
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
biliary cirrhosis (PBC ... ), or with systemic ... lupus erythematosus ... (SLE) Signs / ... Xeroderma (Dry skin
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... lupus erythematosus ... Seizures • Strokes Skin ... #Lupus #Erythematosus
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Lupus - with Systemic ... Lupus Erythematosus ... like “butterfly rash
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... lupus erythematosus
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... Herald's atch • Tinea ... soles • Discoid Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... : erythematous nodules ... mucositis - Rash ... lupus erythematosus ... : strong sign of