1023 results
Carbonic Anhydrase Inhibitor Pharmacology
- Loss of NaHCO3
- Metabolic acidosis
- Tolerance develops after 2-3 days

#Carbonic #Anhydrase #Inhibitor
Anhydrase Inhibitor Pharmacology ... Metabolic acidosis - Tolerance ... Anhydrase #Inhibitor #Pharmacology
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
- Dependence, tolerance ... Benzodiazepines #Psychiatry #Pharmacology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
using highest dose tolerable ... Indications #Titration #Pharmacology
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Naive vs Opioid Tolerant ... Combinations of Non-Pharmacologic
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
- Improved GI tolerance ... Table #Comparison #Pharmacology
Insulin Dosing Basics - Initiating Insulin for T2DM and Converting Insulin Products 

Insulin dosing can be
lack of cross tolerance ... #Prescribing #Pharmacology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
reduced exercise tolerance ... endomyocardial biopsy Pharmacology ... management #cardiology #pharmacology
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
Fluconazole - Low cost/tolerable ... efficacious and tolerable ... half-life, and tolerable ... comparison #table #pharmacology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
but is a very tolerable ... Renal #Dosing #Pharmacology
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis
Fluconazole
 - Benefits: Low cost/tolerable
Benefits: Low cost/tolerable ... efficacious and tolerable ... half-life, and tolerable ... Coccidioidomycosis #pharmacology