32 results
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
tenderness • Positive one-legged ... XR — scotty dog sign ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... , Fragile bones/ ... easily/weakness, Bone ... /joint pain Psychiatric ... Secondary #Tertiary #pathophysiology
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... blade of grass sign ... ) • Enostosis/bone ... docskalski #Knee #Bone ... #XRay #msk #lesions
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Tropheryma whipplei Symptoms ... and Signs: 1. ... - Either one of ... specimen OR • One ... #diagnosis #algorithm
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
different types of bone ... • Aneurysmal bone ... blade of grass sign ... Differential #Diagnosis #Radiology ... #XRay #MSK #pediatrics
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... of bacilli to bone ... CXR should be done
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... onto lateral hip Signs ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms