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diagnosis hematology hlh lymphohistiocytosis lupus sle summary syndrome activation anticoagulation behcet comparison druginduced duration dvt erythematosus hemeonc length macrophage mas
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
acquired forms of haemophagocytic ... A subset of hemophagocytic ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Manifestations: Malar ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... or autoimmune disease ... for refractory disease ... EricsMedicalLectures/ #HLH #Hemophagocytic ... #management #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
life-threatening • Treatment ... Usual therapeutic management ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... sinus thrombosis, VTE ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease • Superficial Venous Thrombosis • Upper
Thromboembolic Disease ... DeLoughery @Bloodman #VTE ... anticoagulation #duration #management ... #DVT #hematology ... #length #treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... recognition and management ... ▪ Autoimmune diseases ... #HLH #Hemophagocytic ... #Hematology #HemeOnc
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