10 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... , PM/SSc OS, MCTD ... anti-Su/Ago • Golgi/polar ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential
Mediastinal Widening - Differential Diagnosis

 • Vascular: Aortic dissection, Aortic anourysm, Enlarged pulmonary arteries, Venous or
Mediastinal Widening - Differential ... ex: duplicated SVC ... Lymphadenopathy • Pericardial ... Pneumomediastinum, Pericardial ... Mediastinal #Widening #Differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
B19 infection Malar ... Antiphospholipid-antibody ... #skin #rashes #differential
Causes of Acute Pericarditis:

Infectious;

Viral: 
Adenovirus 
Coxsackie virus A and B 
Echovirus 
Epstein-Barr virus 
Hepatitis 
Human immunodeficiency
Trauma: Direct pericardial ... catheterization) Pericardial ... leakage into pericardial ... sac) Chylopericardium ... #Pericarditis #Differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... Auto-antibodies: ANCA antibody ... , Anti-GBM antibody ... EGPA (↓ LVEF, pericardial ... Renal #Syndromes #differential
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... , PBC/SSc OS, PBC ... anti-Su/Ago Golgi/polar ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... or scleroderma (SSc ... rheumatology #diagnosis #differential
Mediastinal Mass - Differential Diagnosis Framework

Anterior Mediastinal Mass - 5T’s
 • Thymic neoplasm
 • Teratoma (or
Mediastinal Mass - Differential ... grow through the sac ... - Pericardial ... out-pouching" of the pericardium ... Mediastinal #Mass #Differential
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... , PM/SSc OS, MCTD ... , PBC/SSc OS • ... #Antinuclear #Antibody ... Nuclear #Patterns #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Serositis: • Pleural/pericardial ... Photosensitivity • Malar