13 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... anti-Su/Ago • Golgi/polar ... #differential #
Mediastinal Widening - Differential Diagnosis

 • Vascular: Aortic dissection, Aortic anourysm, Enlarged pulmonary arteries, Venous or
Mediastinal Widening - Differential ... ex: duplicated SVC ... Lymphadenopathy • Pericardial ... Pneumomediastinum, Pericardial ... Mediastinal #Widening #Differential
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... or scleroderma (SSc ... Antibodies #ANA #patterns ... rheumatology #diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... or scleroderma (SSc ... rheumatology #diagnosis #differential
Causes of Acute Pericarditis:

Infectious;

Viral: 
Adenovirus 
Coxsackie virus A and B 
Echovirus 
Epstein-Barr virus 
Hepatitis 
Human immunodeficiency
Trauma: Direct pericardial ... catheterization) Pericardial ... leakage into pericardial ... sac) Chylopericardium ... #Pericarditis #Differential
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Testing - Nuclear Patterns ... Homogeneous pattern ... : • SSc, PBC/SSc ... : • SSc, PM/SSc ... #differential #
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Testing Cytoplasmic Patterns ... , PBC/SSc OS, PBC ... anti-Su/Ago Golgi/polar ... #Cytoplasmic #Patterns ... #differential #
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... EGPA (↓ LVEF, pericardial ... • IF staining patterns ... Renal #Syndromes #differential
Mediastinal Mass - Differential Diagnosis Framework

Anterior Mediastinal Mass - 5T’s
 • Thymic neoplasm
 • Teratoma (or
Mediastinal Mass - Differential ... grow through the sac ... - Pericardial ... out-pouching" of the pericardium ... Mediastinal #Mass #Differential
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
Segment Elevation - Differential ... Early-repolarization pattern ... leads • S1Q3T3 pattern ... Prinzmetal's Angina: • Epicardial ... Segment #Elevation #differential