73 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminases / Transaminitis ... Metabolic: Wilson Disease ... • Autoimmune hepatitis ... images/10587 #Transaminitis ... Transaminases #hepatitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
normal - Ischemic Hepatitis ... > 20x normal - Acute ... Viral Hepatitis ... , Toxic Hepatitis ... hepatology #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Chronic Viral Hepatitis ... Hepatopathy • Acute ... Viral Hepatitis ... Diagnosis #hepatology #transaminitis
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe Acute ... Injury - Ichemic hepatitis ... - Acute biliary ... - Autoimmune hepatitis ... - Wilson disease
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... Syndrome, Celiac Disease ... , Infiltrative Disease ... Diagnosis #Causes #Acute
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... syndrome: - Acute ... Minimal change disease ... Classification #Nephrology ... Recommended Text: Nephrology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Hepatitis B (HBV) Serology

HBsAg - Presence denotes current HBV infection (chronic or acute)
HBV Core Antibody -
Hepatitis B (HBV ... infection (chronic or acute ... Anti-HBcAg IgM - acute ... of active viral disease ... infection #HepatitisB
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... of cholestatic disease ... Alcoholic liver disease ... differential #Hepatology #transaminitis
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Infectious: HIV, Hepatitis ... Syphilis, Lyme disease ... Charcot-Marie-Tooth, Fabry's disease ... , Acute intermittent ... diagnosis #causes #neurology