6 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Hepatopathy • Acute ... 1000): • DILI (Drug-induced ... liver injury) ... Diagnosis #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... #Acute #Chronic ... Cirrhosis #Hepatology #gastroenterology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... EmoryGastroHep #DILI #Drug ... #algorithm #gastroenterology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... #Patterns #Liver ... #LFTs #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injuryliver ... valproate, azoles), Drugs ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... ALF): • Liver ... injury < 26 weeks ... differential #Hepatology #transaminitis ... #LFTs #RValue #