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diagnosis hepatology differential algorithm injury management abnormal aclf chemistry chronic cirrhosis dili elevated failure function hepatitis hepatocellular idiosyncratic induced interpretation
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Hepatopathy • Acute ... 1000): • DILI (Drug-induced ... Function #Tests #LFTs ... Diagnosis #hepatology #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... 15X ULN - Drugs ... Alcoholic Hep, Drugs ... Burak @kwburak #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... EmoryGastroHep #DILI #Drug ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Patterns #Liver ... Injury #hepatology #LFTs ... #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... valproate, azoles), Drugs ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Hepatocellular - Check Acute ... Mixed - Check Acute ... differential #Hepatology #transaminitis ... #LFTs #RValue #
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... Hepatitis (AAH) Drug-Induced ... EmoryGastroHep #ACLF #Acute ... Cirrhosis #Hepatology #gastroenterology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook Presentation: • Epigastric abdominal pain (90%, characteristically
Acute Pancreatitis ... surgery, Trauma, Drugs ... Lipase, Ca2+, LFTs ... #Pancreatitis #Acute ... Management #Treatment #Gastroenterology
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