13 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute leukemia ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... low-risk disease • Indications ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... • Infections: Chronic
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Dosing: 250 mcg tablet ... 2019 COPD GOLD guidelines ... recommendations for the treatment ... severe COPD with chronic ... the use of this medication
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Antithyroid medications ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... Tolvaptan) • Treatment ... #Pharmacology #Medications ... #Table
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... Recurrent and chronic ... signs #symptoms #rheumatology