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hematology diagnosis management algorithm chronic cll lymphocytic mds myelodysplastic anemia aplastic borderline bpd cancer differential disorder effectiveness evidence gastroenterology hemeonc
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute leukemia ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Summary of meta-analysis of pharmacotherapy trials in BPD https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder Meta-analyses of RCTs were undertaken for the following outcomes:
with ‘treatment ... summarised in Tables ... 5.2 and 5.4 #EBM ... Personality #Disorder #Medications ... Effectiveness #Table
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... low-risk disease • Indications ... for Treatment: ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Antithyroid medications ... ) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
workup, including BM ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... factor (GCSF) treatments ... #diagnosis #hematology ... #oncology
Probiotics Guidelines Adults with C difficile infection • Recommendation: Only in the context of a clinical trial
Probiotics Guidelines ... on antibiotic treatment ... irritable bowel syndrome ... #Probiotics #Guidelines ... management #evidence #ebm
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... acute myeloid leukemia ... Network (NCCN) guidelines
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