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diagnosis hematology differential oncology rheumatology acne acromegaly anemia antinxp2 antinxp2dm aplastic cardiology chagas clinical coagulation comparison complexes dermatomyositis dic disease
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
• Antipyretics block ... antipyretics to block ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... comparison #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ab to AChR blocks ... thyroid, Sjogren syndrome ... muscles: “myasthenic crises ... Myasthenia Crises ... Gravis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
(e.g., long QT syndrome ... heart disease Causes ... Bundle branch block ... tachycardia • Bigeminy, Trigeminy ... more intensive treatment
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Most common extra cutaneous ... Causes: - Idiopathic ... Treatment: - Systemic ... #diagnosis #dermatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
involvement (2%) Cutaneous ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Digital ischemia • Cutaneous ... Goodpasture's cause ... differential #diagnosis #management ... #treatment
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