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diagnosis algorithm liver transaminitis causes hematology abnormal adjusted apml biliary cardiology chemistry cholangitis congenital ddimer differentiation dimer forms function hepatitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
European descent • Age ... 65 years PBC Pathophysiology ... normal or slightly elevated ... bile ducts Differential ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... specificity to elevated ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... : • Advanced age-arteriosclerosis ... - Obesity - Cirrhosis ... overdrive • Elevated ... #Diagnosis #Pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... if WBC > 5 or elevated ... initiation • Differential ... diagnosis #management #hematology
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
Elevated plasma ... increase with age ... - Age (yrs) x 10 ... Ddimer #dimer #pathophysiology ... #hematology #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... specificity to elevated ... NT) - If both are ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Inherited forms of Hyperbilirubinemia Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
UB and CB forms are ... Unconjugated Crigler-Najjar ... Hyperbilirubinemia #pathophysiology ... #congenital #hepatology ... #pediatrics #peds
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