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diagnosis hematology syndrome cop differentiation fistula hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis oncology organizing pneumonia pulmonary summary tls tumor vascular
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... unless severe APLS ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Cryptogenic Organizing ... Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... Males=Females SIGNS ... Pneumonia #diagnosis #management
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
Aortoenteric Fistula ... duodenum Clinical Signs ... Pathophysiology: ... bowel, usually as ... Residency @CMC_IM #Aortoenteric
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • In all patients ... Presentation • Common Signs ... Pathophysiology ... Approach • Initial management
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