30 results
Causes of Bradykinetic Movement Disorders - Differential Diagnosis Algorithm
Parkinson's Disease (TRAP):
• Resting Tremor
• Cogwheel Rigidity
• Akinesia/Bradykinesia
•
Bradykinetic Movement Disorders ... Differential Diagnosis Algorithm ... Parkinson's Disease ... • Cerebellar signs ... MovementDisorders #Neurology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Lysosomal storage disorder ... in GBA1 gene Clinical ... #Diagnosis #Signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
An Algorithm for the Management of Seizures

The management of active seizures is algorithmic, starting with a
the Management ... Seizures The management ... and bag-valve mask ... continuous vital sign ... #Neurology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... recessive blood disorder ... The underlying pathophysiology ... Can be triggered ... Crisis #Features #Signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... decreased reflexes Pathophysiology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... Pathogenesis and Clinical ... variability in disease ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... mainly AQP4-lgG disease ... Comorbid autoimmune disorders ... Manifestations #diagnosis #neurology ... #symptoms #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... , PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Person Syndrome Pathophysiology ... Clinical Manifestations ... limb or joint disorders ... #treatment #neurology