7 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... #gastroenterology ... #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... sepsis), PE, DAH, CHF ... #hematology #oncology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... improvement in symptoms ... iron #deficiency #CHF ... heartfailure #diagnosis #management ... #cardiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... the brain • CSF ... Syndrome #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... inflammation: CSF ... Myelitis #diagnosis #management ... #neurology #differential