31 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... into serum • Triggers ... Syndrome #TLS #diagnosis ... #management #hematology
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Gastroesophageal Reflux Disease ... Summary GERD: Diagnosis ... reduction • Avoid “trigger ... Gastroesophageal #Reflux #Disease ... #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
gastrointestinal 4) Primary ... extrapulmonary disease ... or meningitic disease ... Aspergillosis Pathophysiology ... #Management #Infections
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
meningovascular disease ... ulcerated • MSK ... infected without symptoms ... Syphilis #stages #diagnosis ... #management #Treatment
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
variability in disease ... normal mood - Primary ... treatment goal ... #Pathophysiology ... #Signs #Symptoms
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
Clinical Signs/Symptoms ... Pathophysiology: ... also important Management ... data • Early treatment ... #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Primary Progressive ... Multiple Sclerosis Treatment ... #management #neurology ... #treatment #MS
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... : ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... assessment+++ Primary ... • Autoimmune diseases ... Unknown cause Treatment ... #management #treatment
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... , neoplastic) TREATMENT ... steroids for severe disease ... #management #pulmonary