8 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... Syndrome: • Pathophysiology ... into serum • Triggers ... #diagnosis #management
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Gastroesophageal Reflux ... Testing Ambulatory reflux ... reduction • Avoid “trigger ... Gastroesophageal #Reflux ... Disease #diagnosis #management
GERD and Recommended Lifestyle Modifications
 • Avoid fatty meals
 • Avoid carbonated beverages
 • Avoid citrus,
GERD and Recommended ... citrus, if it triggers ... symptoms • Eat ... #reflux #acid # ... Modifications #management
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Obstruction with GERD ... Can also occur after ... injury (by acid reflux ... melena - Other GI symptoms ... Necrosis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... unless severe APLS ... APML #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... neurology #diagnosis #management
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... usually misdiagnosed as ... CAP • Symptoms ... Pneumonia #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • In all patients ... Common Signs and Symptoms ... Pathophysiology ... Approach • Initial management