38 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... lipolysis Signs/Symptoms ... metabolic abn #GrowthHormone ... #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
growth hormone (GH ... The condition is ... Acromegaly #Signs #Symptoms ... #Diagnosis #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... malignancy Pathophysiology ... MRI+contrast Management ... #Endocrinology ... #Treatment #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... Lysis Syndrome: • Pathophysiology ... into serum • Triggers ... TLS #diagnosis #management
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
environmental triggers ... expression - Age: GCA is ... old; F>M Signs/Symptoms ... Temporal #Arteritis #Pathophysiology ... Diagnosis #Signs #Symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
all sizes, it is ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Symporter) but is ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
of hCG, which is ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Dizziness and Vertigo Algorithm
Presyncope:
 • Feels "faint" or like they are going to "pass out"
 •
"pass out" • Symptoms ... may be triggered ... Feels like "room is ... spinning" • Symptoms ... diagnosis #neurology #management