27 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... permeability Diagnosis ... #neurology #rheumatology ... #management #treatment
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... Imaging (if atypical symptoms ... pathology) • LP ... sarcoid or other CNS ... #Neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis of tumor cells ... into serum • Triggers ... Syndrome #TLS #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... Constitutional symptoms ... constitutional symptoms ... comparison #table #rheumatology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... the study) • Triggers ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
PO4 -> decr RBC ATP ... - anemia - CNS ... Refeeding #Syndrome #diagnosis ... #pathophysiology ... #symptoms #signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... tests ↑ AST ↑ ALT ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology