10 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... • Triggers: Diuretics ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... : Unknown trigger ... Females SIGNS/SYMPTOMS ... • Symptoms: Cough ... Pneumonia #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... tendency to fall • Triggers ... • Normal ESR, CRP ... SPS #Diagnosis #Management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... adjuvant Tx, or post-op ... #Endocrinology ... #Treatment #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Common Signs and Symptoms ... Pathophysiology ... #Hematology #HemeOnc
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
cell lymphoma Pathophysiology ... and the systemic symptoms ... levels - Increased CRP ... TAFRO #diagnosis #management ... #rheumatology #
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) Pathophysiology ... calcium to form CPP ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... Nonspecific ↑ ESR, CRP ... Polychondritis #rheumatology ... #diagnosis #management