26 results
diagnosis oncology disease hemophagocytic lymphohistiocytosis rheumatology syndrome algorithm arteritis chronic gastroenterology giantcell leukemia lymphocytic pneumonia summary temporal acquired anorexianervosa aplastic
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... environmental triggers ... HLA-DR4 mutation ... - Normocytic Anemia ... Temporal #Arteritis #Pathophysiology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... stem cell transplant ... #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... varies depending on trigger ... autoimmune disease, treatment ... #Treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
signs and symptoms ... Low or absent NK cell ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... of anemia or thrombocytopenia ... marrow failure with anemia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
cases Clinical Signs ... years - May have signs ... pulmonary TB PE ... decreased reflexes Pathophysiology ... should be done in ALL
Gastroesophageal Reflux Disease (GERD) - Summary GERD: Diagnosis • Heartburn (substernal burning sensation) and acid regurgitation • Chest pain Extraesophageal
Laryngeal and pulmonary ... • Vomiting • Anemia ... Alarm features: • Anemia ... reduction • Avoid “trigger ... Disease #diagnosis #management
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