11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Diagnosis Framework ... cells per μL • Diagnosis ... Multiple infections are ... status, and focal neurologic ... #differential #diagnosis
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... and infects the CNS ... • Depressive symptoms ... Diagnosis: MRI ... dementia #AIDS #Neurology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
regeneration, diffuse CD8 ... primarily deltoids and hip ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 2 hit mechanism ... ARDS to explain symptoms ... Risk factors: Age ... Reactions #hematology #diagnosis ... #comparison #table
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Herpesviruses (MCC: HSV ... Coltivirus Symptoms ... and meningismus are ... #neurology #meningitis
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... equina syndrome (CES ... Differential Diagnosis ... cord infarct • HIV ... #causes #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Takayasu: • Age ... temporal artery • Age ... • Progressive symptoms ... chorioretinitis, CNS
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
immunodeficiency virus (HIV ... bulbar muscles DIAGNOSIS ... than one after symptom ... the underlying pathophysiology ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
peaks between the ages ... monophasic Pathophysiology ... that results in CNS ... simplex virus, HIV ... #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Microglial cells are ... fasciculations Common Symptoms ... motor neurons - IV ... Lateral #Sclerosis #neurology