15 results
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Trauma to the long bone ... stabilization of fractures ... Pathophysiology ... onset widespread pulmonary ... #Signs #Symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... of active pulmonary ... - Local pain at ... decreased reflexes Pathophysiology ... of bacilli to bone
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... pain - Frequent fractures
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
Intensivist's One-Page ... Infection: Coronavirus Disease ... emergency 2020-3-12 Diagnosis ... unilateral* • POCUS ... #Cheatsheet #Diagnosis
Paget’s Disease: Pathogenesis and Clinical Findings

 • Incr serum CTx - marker of bone resorption
 •
Paget’s Disease: ... , kyphosis and fractures ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... , humeral head fracture ... Severe, worse at ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... decreased muscle tone ... compression by fractured ... Sarcoidosis, Behcet disease ... spinalcord #disorders #diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
body • Bird and bat ... extrapulmonary disease ... or meningitic disease ... Encapsulated yeast • At ... Aspergillosis Pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... -> Pathologic fractures ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Mean age at Dx ... age 70 years Symptoms ... Myeloproliferative Disease ... characteristic feature ... Myelodysplastic #Syndromes #diagnosis