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management differential infections infectiousdiseases syndrome antigbm basement cryptogenic encephalopathy fungal giomeruiar goodpastures hematology hemeonc hemophagocytic hiv hlh lung lymphohistiocytosis membrane
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... , neoplastic) TREATMENT ... TylerLarsenMD #COP ... #management #pulmonary
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... antibodies -> Anti-Cyclic ... -> High serum CRP ... RheumatoidArthritis #RA #pathophysiology ... #diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Person Syndrome Pathophysiology ... autoimmune response gone ... • Normal ESR, CRP ... #Management #treatment ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Transplantation including bone ... Etiology: • Pathophysiology ... #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... Elevated ESR and CRP ... affects the skin, neurologic ... cognitive impairment, neurologic
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
extrapulmonary disease ... or meningitic disease ... yeast • At risk: AIDS ... Aspergillosis Pathophysiology ... : • Serology for
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
hemorrhage Diagnosis ... in one of the following ... kidney biopsy Treatment ... Goodpastures #AntiGBM #diagnosis ... #nephrology #pulmonary
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... AntiCRMP IgG, Anti-Hu ... Transverse Myelitis Treatment ... #management #neurology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
- Differential Diagnosis ... Framework Disease ... • CT: Halo sign ... Infections #HIV #AIDS ... #pulmonary #differential
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Autoimmune diseases ... Presentation • Common Signs ... Pathophysiology ... Hemophagocytosis in bone ... JAK inhibitors, anti-IFN-γ
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