19 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... • Bone marrow ... only curative treatment ... #Management #treatment ... #hematology #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management Summary ... Hypercellular bone ... present, symptoms, signs ... #Management #Summary ... #treatment #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management Summary ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... of bacilli to bone
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Symptomatic anemia Diagnosis ... with hypocellular bone ... #management #treatment ... #hematology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... and Management Summary ... Pathophysiology ... dermis Clinical Signs ... #Management #dermatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... • A clinical diagnosis ... and lower jaw Treatment ... #diagnosis #management ... #Dermatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Hemophagocytosis in bone ... • Bicytopenia Treatment ... #management #treatment ... #hematology