63 results
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... • Spurling's sign ... pain Lasegue's sign ... MSK #diagnosis #signs ... #symptoms #pathophysiology
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
clinical findings Abnormal ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology ... #symptoms #signs
Functional Dyspepsia - Signs, Symptoms and Pathophysiology
Delayed gastric emptying - Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric
Functional Dyspepsia - Signs ... , Symptoms and Pathophysiology ... Atypical nonerosive reflux ... disease - Epigastric ... #diagnosis #signs
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Disruption of normal ... osteophyte with normal ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology ... of bacilli to bone
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Proximal Weakness, Normal ... Weakness, Incr CK • Bone ... hydroxychloroquine therapy), Normal ... Complications #pathophysiology ... #signs #symptoms
Orbicularis Reflex in an Alzheimer's Patient on Physical Exam

Alzheimer's is a degenerative, progressive and irreversible disease.
and irreversible disease ... One of the first ... symptoms is the ... examination is usually normal ... clinical #video #neurology