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diagnosis differential nephrology causes management hematology oncology classification high hyperkalemia potassium renal table algorithm anemia blood cll copper deficiency diuresis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... anemia Treatment
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
GI losses - Chronic ... Renal Loses - Medications ... renal Mg wasting syndromes ... - Gitelman syndrome ... syndrome Dr.
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... formed or don’t work ... Causes • Anemia • Aplastic ... Marrow Failure • Chronic
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Malabsorption, Chronic ... alkalosis, Hungry bone ... syndrome, Tumor ... genesis syndrome ... FGF-23: Fanconi syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Pure red cell aplasia ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Prostate cancer • Medications ... (Goodpasture's syndrome ... FSGS • Other: Chronic ... urine #management #treatment ... #nephrology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... • Infections: Chronic
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... and nephrotic syndrome ... disease • Liddle syndrome ... Tolvaptan) • Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... syndrome by 24 ... Paraneoplastic syndrome ... Encephalopathy #Syndrome
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
bowel disease, Chronic ... diarrhoea, Short bowel syndrome ... Cystic fibrosis • Medications ... dental fixatives, Treatment ... Musculoskeletal: Low bone
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