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diagnosis differential hematology management oncology mds myelodysplastic acidosis cauda caudaequina chronic classification cll disorders elevation encephalopathy equina gbs guillain hearing
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... CMV) • Epstein-Barr ... anemia Treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... • Bone marrow
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... • Anemia • Aplastic ... Anemia • Bone ... Workup: • Complete
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Hypothyroidism • Medication-induced ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... differential #diagnosis #causes ... #neurology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... family history - Medications ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... candidate) - Bone
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... evaluation should be done ... Neurologic disorders ... , and Guillain-Barre ... #Hypertension #Workup
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... and cauda equina TREATMENT ... #Syndrome #diagnosis ... #management #neurology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... Warm AIHA • Bone ... Leukemia #diagnosis #workup
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Transplantation including bone ... Electrolyte abnormality, Medication ... the underlying cause ... • Treatment of
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
- Emergency Causes ... cord • Guillain-Barre ... decreased rectal tone ... axial T1 and T2 Treatment ... #neurology
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