70 results
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
Triquetral Fracture ... The triquetrum ... fractured carpal bone ... common carpal bone ... #Orthopedics #Sports
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
the articular bone ... Peri-articular osteopenia (bones ... Diagnosis #Radiology #Clinical ... #Pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology
Osteoarthritis (OA): X-ray features 
 - Joint space narrowing (least specific)
 - Subchondral Cysts (pockets of
Osteophytes (Abnormal bone ... deposits/spurs ... (Thickening of bone ... under the areas of bone-bone ... diagnosis #findings #Clinical
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... • Deletion of critical ... Infertility • Decr Bone ... fractures • Short ... Syndrome #genetics #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • softening of bones ... of feet, thigh bones ... Neuropathy ALP is critical ... collection with EDTA Pathophysiology
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Pathogenesis and Clinical ... insertion into bone ... , ridging, oil spots ... PsoriaticArthritis #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... deficiency: - Short ... endocrinology #pathophysiology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... Rheumatic pain Clinical ... • Bone and joint ... anterior chest wall, parts ... Diagnosis: • A clinical