19 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... ) - Differential ... Ig deposition disease ... Diagnosis #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • XR, MRI to ... • Differentiate ... #differential # ... diagnosis #causes #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... more: • Clonal bone ... focal lesions on MRI ... #Gammopathies #MGUS ... #diagnosis #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rheumatic pain Clinical ... - MRI: inflammation ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
and Management Summary ... Clinical features ... CT/MRI of the thorax ... Bone scan is indicated ... patients with bone
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... and Management Summary ... extrapulmonary cases Clinical ... of bacilli to bone ... Diagnosis: - MRI
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease ... fragmentation and mild bone ... • MRI is more sensitive ... tibial tuberosity Differential ... #mri #clinical
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
prior signs or clinical ... surgeon had a clinical ... Differential diagnosis ... diffuse chondral disease ... diagnosis #msk #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... management #treatment #summary ... #rheumatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... osteoclast activity and bone ... resorption - Bone ... Ig deposition disease ... rituximab (in clinical