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diagnosis management hematology hemophagocytic hlh lymphohistiocytosis neurology treatment acromegaly als amyloid amyloidosis amyotrophic carcinoma chronic cll dermatology encephalopathy endocrinology hemeonc
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rheumatic pain Clinical ... - MRI: inflammation ... osteoarticular and skin disease ... #Rheumatology #
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... extrapulmonary cases Clinical ... decreased reflexes Pathophysiology ... of bacilli to bone ... Diagnosis: - MRI
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
and Management Summary ... Clinical features ... Budd Chiari syndrome ... CT/MRI of the thorax ... patients with bone
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... management #treatment #summary ... #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Transplantation including bone ... Etiology: • Pathophysiology ... Vascular narrowing on MRA ... Reversible course Differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... cells can indicate disease ... Warm AIHA • Bone ... • Richter’s Syndrome
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
and Management Summary ... GrepMed Handbook Clinical ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... • Pituitary MRI
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Sclerosis (ALS) Summary ... lateral sclerosis Pathophysiology ... Presentation: - Disease ... MRI: Brain, cervical ... conditions listed in differential
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Amyloidosis - Summary ... Clinical suspicion ... the extent of disease ... muscle wasting Bone ... enlargement • MRI
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Autoimmune diseases ... Clinical Presentation ... Pathophysiology ... Hemophagocytosis in bone ... Diagnosis #Management #Hematology
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