36 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Screen for HLH ... HLH syndrome 5. ... Alcoholism Bone ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... pulmonary disease ... multifactorial mechanisms Hematologic ... Hypertension #PHTN #Classification
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Screen for HLH ... HLH syndrome 5 ... Alcoholism Bone ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... Adult-onset Still disease ... Lymphohistiocytosis #diagnosis #management
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
Pulmonary vasculature ... Diseases of the ... HPS-severity classification ... Syndrome #HPS #hepatology ... #pulmonary #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... CD163 staining of bone ... is found in the bone ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... age, however the disease ... Hemophagocytosis in bone ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... autoinflammatory diseases ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Chronic Obstructive Pulmonary Disease (COPD)
 • COPD Definition
 • Role of PFTs
 • COPD Classification and
Chronic Obstructive Pulmonary ... Disease (COPD) ... PFTs • COPD Classification ... #Disease #COPD ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... anymore • Routine bone ... number of sites of disease ... #hematology #oncology ... #management