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differential treatment signs algorithm hematology neurology rheumatology pathophysiology gastroenterology msk endocrinology hepatology oncology dermatology nephrology summary chronic complications nutrition table
Primary and Secondary Causes of Osteoporosis Primary osteoporosis - idiopathic juvenile osteoporosis - postmenopausal
and Secondary Causes ... Cushing syndrome ... intolerance Bone ... plasmacytoma) - diffuse bone ... Differential #Endocrine #Diagnosis
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Osteoporosis: Pathogenesis ... 30 (post-peak bone ... Decr estrogen • Bone ... pathophysiology #signs #symptoms ... #diagnosis
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
- Differential Diagnosis ... Tumours - See Bone ... • Bone Marrow ... #Differential #Diagnosis ... #Orthopedics #Causes
Vertebral Body Abnormalities A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
Vertebra Hurler Syndrome ... Morquio Syndrome ... Sclerotic Mets Bone ... Schmorl Node Osteopetrosis ... Anomalies #Spine #Diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... important, as early diagnosis ... Inflammatory causes ... #differential #diagnosis
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... Osteonecrosis, bone ... infarcts, osteoporosis ... #Diagnosis #Signs ... #Symptoms
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Most common symptoms ... - Bone symptoms ... #Differential #Diagnosis
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... • Signs and symptoms ... without discernable cause ... • Signs of osteoporosis ... #Diagnosis #Algorithm
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Normal CK • Osteoporosis ... pathophysiology #signs #symptoms ... #diagnosis
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease ... • Caused by ( ... • The disease ... #Bone #diagnosis ... #management #treatment
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