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diagnosis treatment differential pathophysiology hematology neurology algorithm disease oncology rheumatology msk orthopedics checklist dermatology endocrinology gastroenterology psychiatry pulmonary workup anesthesia
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
fractured carpal bone ... "pooping duck sign ... common carpal bone ... "pooping duck sign ... fractures • ED Management
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Osteoporosis: Pathogenesis ... 30 (post-peak bone ... Decr estrogen • Bone ... pathophysiology #signs ... #symptoms #diagnosis
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... , Fragile bones/ ... osteoporosis, Kidney ... easily/weakness, Bone ... pain Psychiatric Symptoms
Primary and Secondary Causes of Osteoporosis Primary osteoporosis - idiopathic juvenile osteoporosis - postmenopausal
and Secondary Causes ... Cushing syndrome ... intolerance Bone ... plasmacytoma) - diffuse bone ... #Secondary #Causes
Budd Chiari Syndrome Hepatic vein obstruction. Can be caused by thrombosis or sometimes a tumour. Can lead
Budd Chiari Syndrome ... Can be caused by ... #BuddChiari #Syndrome ... #Diagnosis #Causes ... #Signs #Symptoms
Marfan Syndrome - Signs and Symptoms - Caused by mutations in the fibrillin-1 (FBN1) Gene (chromosome 15) -
Marfan Syndrome ... - Signs and Symptoms ... - Caused by ... #Diagnosis #Signs ... #Symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Infertility • Decr Bone ... mineral density and osteoporosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Normal CK • Osteoporosis ... pathophysiology #signs ... #symptoms #diagnosis
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced Osteoporosis ... -> Reduced Bone ... Formation, Increased Bone ... pathophysiology #signs ... #symptoms #diagnosis
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Osteonecrosis, bone ... infarcts, osteoporosis ... Disease #Diagnosis #Signs ... #Symptoms
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