39 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... - Highest • Bone ... Most common symptoms ... symptoms - Pain ... #Elevation #Differential
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... collection with EDTA Pathophysiology ... mineralization Symptoms
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... obgyn #diagnosis #management ... #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... Clinical Signs/Symptoms ... decreased reflexes Pathophysiology ... of bacilli to bone ... should be done in ALL
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Symptoms of metastatic ... Bone scan is indicated ... patients with bone ... , and/or ALP 5.
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... suspicious clinical symptoms ... box indicates all ... ALP, alkaline phosphatase ... Liver #Enzymes #Differential
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... improvement in symptoms ... composite endpoint of all-cause ... heartfailure #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... Nucleotidase • ALT ... obstruction • ALP ... bile ducts Differential
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... hepatocellular aerobic ATP ... also includes symptoms ... Toxicology #Diagnosis #Management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Classification #pathophysiology ... Diagnosis #NonHodgkin #differential