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diagnosis msk signs endocrinology growthhormone management radiology wrist acromegaly bone causes complications excess feedbackloop femoralhead femur fracture frequency overproduction pagetsdisease
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
Triquetral Fracture ... carpal bone. ... bone fracture ... Discharge with orthopedic ... #Triquetrum #Fracture
Most Common Carpal Bone Fractures by Frequency • Scaphoid - 50-80% • Triquetral - 5-20% •
Most Common Carpal ... Bone Fractures ... Scaphoid - 50-80% • Triquetral ... #Bone #Fractures ... radiology #msk #orthopedics
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
mechanical loading => Bone ... strain => Bone ... StressFractures #msk #orthopedics ... #pathophysiology ... #symptoms #signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... Incr IGF1 • Bone ... lipolysis Signs/Symptoms ... expansion (e.g. carpal ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... Acne • Coarse features ... diagnosis #signs #symptoms ... endocrinology #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Bisphosphonate suppresses bone ... damage weakens the bone ... #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... lateral hip Signs/Symptoms ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
coarsening facial features ... paresthesias (carpal ... malignancy Pathophysiology ... Differential Diagnosis ... Endocrinology #Treatment #Pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Joint diseases features ... in subchondral bone ... boggy" joints, esp carpal ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
cause excessive bone ... -> Pathologic fractures ... the vertebral canal ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
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