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diagnosis hematology management algorithm hodgkins jugular lemierres leukemia lymphoma myelodysplastic neck neurology otolaryngology rij syndromes thrombosis ultrasound abnormal anemia aplastic
Osteosarcoma Most common primary malignant bone tumor in children Most Common Sites of Involvement: 1. Distal femur
primary malignant bone ... proximal femur Clinical ... injury • Systemic symptoms ... Diagnosis #Features #Oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... myelodysplastic #syndrome ... #differential # ... #dermatology #oncology ... #clinical #skin
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... Noncontiguous spread • Clinical ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Constitutional Syndromes ... Aplastic Anemia Clinical ... • Improve the symptoms ... Aplastic #Anemia #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... capillary leak syndrome ... • Schnitzler syndrome ... Diagnosis #hematology #oncology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Brown-Séquard Syndrome ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... #lesions #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... 3: Necrosis of bone ... inner cortical bone ... pathophysiology #signs #symptoms ... #diagnosis #otology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... age 70 years Symptoms ... megakaryocytic Bone ... blood count with differential ... diagnosis #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... Differentiation #Syndrome ... management #hematology #oncology
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